p-Phenetidine
Also known as: p-Phenetidine (dye intermediate)
INCI: p-Phenetidine | Function: Banned substance (aromatic amine) | Type: Banned substance (aromatic amine)
What Is p-Phenetidine?
p-Phenetidine 是一种芳香胺 (aromatic amine), 用于合成染料和 phenacetin 的化学中间体。具有血液毒性 (methemoglobinemia risk) 和潜在致癌性。EU CosIng Annex II 中列为化妆品禁用物质。
Key Skin Benefits
- + None — banned substance
Pros
- + None — banned substance
Cons
- − BANNED — IARC Group 1/2B carcinogen
- − Severe toxicity risk
- − No safe use in cosmetics
Specifications
| Property | Value |
|---|
| Usage Areas | N/A |
| Product Type | N/A |
| Source | Synthetic |
| Natural Level | Synthetic |
Safety Ratings
| Metric | Rating |
|---|
| Skin Sensitivity | BANNED |
| Comedogenic Rating | N/A |
| EWG Score | 10/10 (BANNED) |
Regional Regulatory Limits
| Region | Leave-on % | Rinse-off % | Status |
|---|
| EU (CosIng) | BANNED | BANNED | Prohibited — Annex II |
| US (CIR/FDA) | BANNED | BANNED | Not permitted in cosmetics |
| Japan (MHLW) | BANNED | BANNED | Prohibited |
| ASEAN | BANNED | BANNED | Prohibited |
| China (NMPA) | BANNED | BANNED | Prohibited |
Typical Usage % by Product Type
| Product Type | Typical % |
|---|
| Not used in cosmetics | N/A — banned |
References
- EU CosIng Database. https://ec.europa.eu/growth/tools-databases/cosing/
- IARC Monographs. https://monographs.iarc.who.int/
- FDA — Withdrawn products. https://www.fda.gov/