Pentaerythrityl Tetra-Di-t-Butyl

What Is Pentaerythrityl Tetra-Di-t-Butyl?

Pentaerythrityl Tetra-Di-t-Butyl (full chemical name: Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate) is a hindered phenolic antioxidant widely used as a stabilizer in cosmetic formulations. It is not an active skincare antioxidant but rather a formulation protectant that prevents oxidation and rancidity of oils, fats, and fragrances in the product. It functions similarly to BHT and tocopherol in protecting product integrity and extending shelf life. The molecule contains four hindered phenol groups attached to the pentaerythritol core.

Key Skin Benefits

• + Product preservation — prevents oxidation and rancidity of oils
• + Shelf life extension — protects formulation from degradation
• + Color stability — prevents yellowing of oil-based products
• + Fragrance protection — preserves volatile scent compounds

Pros

• + Highly effective hindered phenol antioxidant
• + Low required concentration for effective protection
• + Protects both oil and fragrance components
• + Good thermal stability in processing

Cons

• − Synthetic antioxidant — not for natural formulations
• − Not a skincare active antioxidant (formulation protectant only)
• − High molecular weight limits skin penetration (which is actually desirable)
• − Similar regulatory scrutiny as other synthetic antioxidants

Specifications

Safety Ratings

Regional Regulatory Limits

Typical Usage % by Product Type

References

1. CosIng (2025) — Pentaerythrityl Tetra-Di-t-Butyl. https://ec.europa.eu/growth/tools-databases/cosing/
2. EWG Skin Deep — Synthetic antioxidants. https://www.ewg.org/skindeep/
3. Personal Care Products Council — INCI Dictionary