Pentaerythrityl Tetraacetate

INCI: Pentaerythrityl Tetraacetate | Function: Plasticizer, Solvent | Type: Synthetic Ester

What Is Pentaerythrityl Tetraacetate?

Pentaerythrityl Tetraacetate is the fully acetylated ester of pentaerythritol — all four hydroxyl groups are esterified with acetic acid (C2). It is a low-molecular-weight tetraester that functions primarily as a plasticizer in nail polishes and hair sprays, helping prevent film brittleness. Due to its small size and volatile nature, it may also serve as a solvent carrier. It is less commonly used in skincare and more in styling and color cosmetic products.

Key Skin Benefits

Pros

Cons

Specifications

PropertyValue
Usage AreasHair
Product TypeLeave-On, Rinse-Off
SourceSynthetic
Natural LevelSynthetic

Safety Ratings

MetricRating
Skin Sensitivity2/5
Comedogenic Rating0/5
EWG Score2/10

Regional Regulatory Limits

RegionLeave-on %Rinse-off %Status
EU (CosIng)No limitNo limitAllowed
US (CIR/FDA)No limitNo limitAllowed
Japan (MHLW)No limitNo limitAllowed
ASEANNo limitNo limitAllowed
China (NMPA)No limitNo limitAllowed

Typical Usage % by Product Type

Product TypeTypical %
Nail polish plasticizer2 - 8%
Hair spray1 - 5%

References

  1. CosIng (2025) — Pentaerythrityl Tetraacetate. CAS: 597-71-7. https://ec.europa.eu/growth/tools-databases/cosing/
  2. SpecialChem — Plasticizers in cosmetics. https://cosmetics.specialchem.com/
  3. Personal Care Products Council — INCI Dictionary
← Back to Skinpedia