PENTASODIUM AMINOTRIMETHYLENE PHOSPHONATE

Also known as: Pentasodium Aminotrimethylene Phosphonate

INCI: PENTASODIUM AMINOTRIMETHYLENE PHOSPHONATE | Function: Chelating Agent | Type: Synthetic phosphonate chelating agent

What Is PENTASODIUM AMINOTRIMETHYLENE PHOSPHONATE?

Pentasodium Aminotrimethylene Phosphonate is a phosphonate-based chelating agent. Compared to EDTA and phosphate chelators, phosphonates offer superior stability across a wide pH range and better biodegradability. It sequesters metal ions that would otherwise destabilize formulations.

Key Skin Benefits

+ Broad pH range stability (unlike EDTA)
+ Excellent calcium and magnesium chelation
+ Better biodegradability than EDTA
+ Prevents product discoloration and rancidity

Pros

+ Works across wide pH range
+ More biodegradable than EDTA-based chelators
+ Effective at low concentrations

Cons

− Synthetic — not natural
− More expensive than EDTA
− Phosphonate chemistry — environmental discharge considerations

Specifications

Property	Value
Usage Areas	Face, Body
Product Type	Leave-On, Rinse-Off
Source	Synthetic
Natural Level	Synthetic

Safety Ratings

Metric	Rating
Skin Sensitivity	1/5 (very low)
Comedogenic Rating	0/5
EWG Score	2/10

Regional Regulatory Limits

Region	Leave-on %	Rinse-off %	Status
EU (CosIng)	No limit	No limit	Allowed
US (CIR/FDA)	No limit	No limit	Allowed
Japan (MHLW)	No limit	No limit	Allowed
ASEAN	No limit	No limit	Allowed
China (NMPA)	No limit	No limit	Allowed

Typical Usage % by Product Type

Product Type	Typical %
Any water-based formula	0.05 - 0.3%
Cleanser	0.1 - 0.5%
Toner	0.05 - 0.2%

References

CIR — Safety Assessment of phosphonates. PMID: 23781871
EU CosIng Database — Listed as chelating.
SpecialChem — Phosphonate chelating agents overview

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