Perilla Ocymoides Leaf Extract

What Is Perilla Ocymoides Leaf Extract?

Perilla Ocymoides (syn. Perilla frutescens var. crispa) is a botanical synonym for the shiso plant, also known as beefsteak plant. The leaf extract is rich in rosmarinic acid, luteolin, and perilla ketone, providing strong antioxidant and anti-inflammatory benefits. In skincare, it is used to calm irritated skin, reduce oxidative stress from UV and pollution, and support barrier function. It is a popular ingredient in Asian cosmetic formulations for sensitive and reactive skin types.

Key Skin Benefits

• + Rosmarinic acid — potent anti-inflammatory for redness reduction
• + Flavonoid antioxidants — luteolin and apigenin protect against free radicals
• + Anti-allergic activity — inhibits IgE-mediated histamine release
• + Pollution defense — chelates heavy metals and neutralizes particulate-induced ROS

Pros

• + Botanically identical to Perilla Frutescens — same active profile
• + Gentle enough for hypersensitive skin types
• + Long history of safe use in food and traditional medicine
• + Water-soluble extract — easy formulation integration

Cons

• − Extract standardization varies by supplier
• − Limited published cosmetic-specific clinical trials
• − Natural color may vary batch to batch
• − Avoid in mint-family allergies

Specifications

Safety Ratings

Regional Regulatory Limits

Typical Usage % by Product Type

References

1. CosIng Database — Perilla Ocymoides Leaf Extract. https://ec.europa.eu/growth/tools-databases/cosing/
2. Takano H et al (2004) — Anti-allergic effects of perilla extract. PMID: 15284824
3. EWG Skin Deep — Perilla Ocymoides Leaf Extract. https://www.ewg.org/skindeep/