Phenylethyl Resorcinol
Also known as: SymWhite 377
INCI: Phenylethyl Resorcinol | Function: Brightening | Type: Resorcinol derivative / Tyrosinase inhibitor
What Is Phenylethyl Resorcinol?
Phenylethyl Resorcinol (商品名 SymWhite 377) 是一种高效的酪氨酸酶抑制剂, 由德国 Symrise 公司开发。其美白效果据称是 kojic acid 的 22 倍, β-arbutin 的 100 倍以上。通过竞争性抑制 tyrosinase 活性阻断 melanin 合成, 是目前高端美白护肤品中最有效的活性成分之一。
Key Skin Benefits
- + Potent tyrosinase inhibition — 远超 kojic acid
- + Melanin synthesis blockade
- + Clinically proven
- + High stability
Pros
- + One of the most effective tyrosinase inhibitors
- + Clinically demonstrated
- + Stable molecule
- + Symrise patented
Cons
- − Relatively expensive
- − May cause mild irritation
- − Not during pregnancy
- − China limit 0.5%
Specifications
| Property | Value |
|---|
| Usage Areas | Face, Eye, Body, Hair |
| Product Type | Leave-On, Rinse-Off |
| Source | Synthetic |
| Natural Level | Synthetic |
Safety Ratings
| Metric | Rating |
|---|
| Skin Sensitivity | 1-2/5 |
| Comedogenic Rating | 0/5 |
| EWG Score | 2/10 |
Regional Regulatory Limits
| Region | Leave-on % | Rinse-off % | Status |
|---|
| EU (CosIng) | No limit | No limit | Allowed |
| US (CIR/FDA) | No limit | No limit | Allowed |
| Japan (MHLW) | No limit | No limit | Allowed — quasi-drug registration for whitening |
| ASEAN | No limit | No limit | Allowed |
| China (NMPA) | 0.5% | N/A | Allowed — max 0.5%, registered whitening ingredient |
Typical Usage % by Product Type
| Product Type | Typical % |
|---|
| Whitening serum | 0.1–0.5% |
| Dark spot corrector | 0.1–0.5% |
References
- EU CosIng Database. https://ec.europa.eu/growth/tools-databases/cosing/
- Symrise — SymWhite 377 technical dossier. https://www.symrise.com/
- Gillbro JM et al. (2015) — Tyrosinase inhibitors. PMID: 26016659